Stefan Cassadine - Patriarch of the Cassadine family, he retains control of the family assets until his eldest son Nikolas comes of age.

Alexis Davis - Half-sister of Stefan, she acts as his attorney and trusted advisor.

Helena Cassadine - Mother of Stefan and Stavros, she desires exclusive control of the Cassadine fortune and power, and will use both Nikolas and Andresj' to get it.

Nikolas Cassadine - Long believed to be the son of Stavros Cassadine and heir to the Cassadine dynasty, he is in fact the elder son of Stefan Cassadine and Laura Spencer.

Andresj' Cassadine - Adopted son of Stefan, he is slightly younger than Nikolas and has his eye on an older woman.

Keesha Ward - Cousin of Justus Ward, and the ex- of both Jason and AJ Quartermaine, she is in charge of Ward House since her grandmother's death.

Justus Ward - Grandson of jazz singer Mary Mae Ward and Edward Quartermaine (patriarch of the affluent Quartermaine family).